Confirmation of the Rosenow antibody-antigen skin reaction in idiopathic epilepsy.

Rosenow (1947b) has reported the isolation of an immunologically identifiable strain of alpha streptococcus from patients with idiopathic epilepsy. He also reports that the intradermal injection of antibodies specific for this strain elicits an erythematous skin reaction in patients harbouring this organism, and in a high percentage of other epileptic patients as well. This paper presents an investigation and a statistical verification of this reaction in epileptic patients in England; antibodies prepared in the United States from organisms isolated there were used.